Share prices in Europe and Asia were mostly lower on Wednesday after the debate between President Donald Trump and his Democratic challenger Joe Biden.

There was scant sign the clash did much to sway investors. Shares fell in Paris, Frankfurt and Tokyo on Wednesday, while upbeat manufacturing data lifted shares in Hong Kong and Shanghai.

Investors remain cautious with COVID-19 infections on the rise again in the U.S. and elsewhere. The Trump-Biden debate occurred as coronavirus deaths worldwide have surpassed 1 million. Many millions of people worldwide are jobless.

Germany’s DAX fell 0.6% to 12,755.33 and the CAC 40 in Paris lost 0.4% to 4,813.99. The FTSE 100 in Britain edged 0.1% lower to 5,889.73. U.S. futures skidded, with the contract for the S&P 500 down 0.8% and that for the Dow industrials falling 0.9%.

A survey of Chinese manufacturers, t he Caixin manufacturing purchasing manager’s index, showed economic activity accelerating further in September as businesses recovered from the downturn earlier this year due to the pandemic.

The Caixin manufacturing PMI